Looks like Trend Micro's the only major AV vendor to miss the WMF exploit-infected files that were pushed through a bevy of AV products for testing yesterday. Symantec & McAfee caught every file, so if you're using one of those, you should be ok if your definitions are up-to-date.

"Several smaller providers of antivirus products also caught all the examples of malicious code, including Sophos, Kaspersky, Computer Associates International, F-Secure and BitDefender."